Post-Translationally Modified Proteoforms as Biomarkers: From Discovery to Clinical Use

Ruben Y Luo, Priscilla S W Yeung, Morgan W Mann, Lichao Zhang, Yifei K Yang, Andrew N Hoofnagle, Post-Translationally Modified Proteoforms as Biomarke...

Embracing Generative Artificial Intelligence as a Support Tool for Clinical Decision-Making

Nicholas C Spies, Embracing Generative Artificial Intelligence as a Support Tool for Clinical Decision-Making, Clinical Chemistry, Volume 71, Issue 11...

Diagnostic Value of Digital Estimates of Trophoblastic Mosaicism in Genome-Wide Cell-Free Fetal DNA Screening

Risk vs Prevalence: Weighing Routine DPYD Variant Testing Prior to Fluoropyrimidine-Based Chemotherapy

Audio Summary November 2025

Optimizing Estimation: Perspective on Drug Dosing Using New CKD-EPI Equations

Audio Summary October 2025

Utilizing the Stability of Individual Homeostatic Setpoints over Time - A Step Forward on the Path to Personalized Laboratory Medicine

Advances in Syphilis Diagnostics to Address the 21st-Century Epidemic

Machine Learning for Detecting Iron Deficiency through Comprehensive Blood Analysis

Toward Improved Prostate Cancer Screening: Insights from the Göteborg-2 Trial

Audio Summary September 2025

Proteomic Aging Clock Predicts Mortality and Risk of Common Age-Related Diseases

Influence of Macrotroponin on the 99th Percentile Threshold in 2 High-Sensitivity Cardiac Troponin Assays

Pulse Oximeter Performance across Populations with Diverse Skin Tones

Polygenic Effects on Hb A1c May Mask Hyperglycemia and Increase Retinopathy Risk

Audio Summary August 2025

Reducing the Noise in Plasma Metagenomics to Further Define Clinical Utility

Correlations Within and Between Highly Multiplexed Proteomic Assays of Human Plasma

Audio Summary July 2025

Robotic Process Automation in Laboratory Medicine

HOPEing That a PEACEful Resolution for the Clinical Utility of High-Sensitivity Cardiac Troponin in the Ambulatory Setting Will Improve Laboratory Testing

Audio Summary June 2025

The Slow Progress in Developing Better Long-Term Cardiovascular Risk Assessment in Women Continues

Pediatric vaccine-induced antibody thresholds: Rethinking pre-immunosuppression serologic testing and revaccination implications

Reevaluating the threshold for low total testosterone

Help Us to Help You: Recommendations for Continued Enforcement Discretion for Common Infectious Disease Test Modifications under the FDA Final Rule

Audio Summary May 2025

New Clinical Practice Guidelines for Vitamin D Supplementation and Testing

Normal Thyroid-Stimulating Hormone and Elevated Free Thyroxine in a Patient Presenting with Self-Reported Heart Palpitations

Cardiac Biomarkers and Malnutrition Incidence in Community-Dwelling Older Adults without Cardiovascular Disease: The Seniors-ENRICA-2 Cohort

Pharmacogenetic Analysis of CYP2C19 for Clopidogrel: Ready for Prime Time

Audio Summary April 2025

A Multianalyte Machine Learning Model to Detect Wrong Blood in Complete Blood Count Tube Errors in a Pediatric Setting

An AI Model (LORIS) to Predict Immune Checkpoint Blockade Response in Cancer: A Clinical Data Science Perspective

Audio Summary March 2025

New American Society of Hematology Thrombophilia Guidelines Could Provoke Surge in Laboratory Testing

Xylazine Pharmacokinetics in Patients Testing Positive for Fentanyl and Xylazine

Rethinking Albuminuria in Low-Risk Patients and a Call for Urine Albumin Standardization

Audio Summary February 2025